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M.Sc. Sharvari Harshe
Doctoral student
Department of Ecology
School of Biology/ Chemistry
University of Osnabrück
Barbarastrasse 13
49076 Osnabrück, Germany
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Research interests
Bacteria, like most organisms on Earth, rarely exist in isolation—they live in dynamic communities and constantly interact with their surroundings. My research focuses on understanding the molecular and ecological basis of these interactions, both between bacteria and their partners, and between bacteria and their environment. During my PhD, I explore whether and how bacteria are locally adapted to their co-occurring partners, using a system of co-isolated auxotrophic and prototrophic soil bacteria. In addition, I investigate cross-feeding interactions between laboratory strains of auxotrophs and prototrophs to better understand the mechanisms underlying microbial cooperation
Education and Scientific Career
2021 PhD student in the Department of Ecology, University of Osnabrück
2018-2019 Project Intern, Mechanobiology institute, National University of Singapore (NUS), Singapore
2018 Master of Science, Department of Cell and Molecular biology, Maharaja Sayajirao University (MSU) India.
2018-2019 Project Intern, Mechanobiology institute, National University of Singapore (NUS), Singapore
2018 Master of Science, Department of Cell and Molecular biology, Maharaja Sayajirao University (MSU) India.
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Master thesis: “Visualizing in vivo Salmonella Typhimurium biofilms in the heterologous host Caenorhabditis elegans”, National University of Singapore (NUS), Mechanobiology Institute.
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2013 – 2018 Integrated Bachelors and Master of Science in Cell and Molecular biology, MSU, Vadodara, India
Publications
2025 G. Yousif, F. Zorrilla, S. Dash, L. Oña, A. Shekhar, S. Giri, R. Guan, Sharvari Harshe, M.Itermann, D. Welter, V. Benes, K.R. Patil, Christian KostbioRxiv 2025.01.29.635426; doi: https://doi.org/10.1101/2025.01.29.635426
2019 S.K. Desai, A. Padmanabhan, S. Harshe, R. Zaidel-Bar, & L.J. Kenney, Salmonella biofilms program innate immunity for persistence in Caenorhabditis elegans, Proc. Natl. Acad. Sci. U.S.A. 116 (25) 12462-12467, https://doi.org/10.1073/pnas.1822018116 (2019).
2019 S.K. Desai, A. Padmanabhan, S. Harshe, R. Zaidel-Bar, & L.J. Kenney, Salmonella biofilms program innate immunity for persistence in Caenorhabditis elegans, Proc. Natl. Acad. Sci. U.S.A. 116 (25) 12462-12467, https://doi.org/10.1073/pnas.1822018116 (2019).
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