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M.Tech. Samir Giri
Doctoral student
Department of Ecology
School of Biology/ Chemistry
University of Osnabrück
Barbarastrasse 13
49076 Osnabrück
Germany
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Research interests
Microbes typically live in diverse, complex communities containing cells of many taxonomic genotypes and species. In such lifestyle microbes frequently interact with multiple genotypes and species in different scales. At these scales, ecological interactions, which can be positive, promote growth and enable collective behaviors that neither partner can perform alone. Or negative decrease growth, survival, and reproduction of microbial populations, directly influence community structure and dynamics. I study the positive interactions in bacteria involving an exchange of essential metabolites for growth known as cross-feeding. Using experimentally tractable bacterial strains as an obligate mutualistic community, I am investigating how different genotypes interact and shape collective metabolism, how Black Queen functions emerge over time within versus between species, and how carbon flux dictates metabolic interactions in bacteria.
- Evolution of ecological interactions in microbial communities
- Genomic and evolutionary consequences of synergistic coevolution
- Collective behaviour of microorganisms
- Evolution and diversity of biosynthetic gene clusters in bacteria
Key words: Metabolic complementation, Cross-feeding interactions, Experimental evolution, Functional specialization, metabolic dependencies, Biochemical conflict, Black Queen functions
Education and Scientific Career
Since 2015 Doctoral research student, Department of Ecology, University of Osnabrück, Osnabrück, Germany and
International Max Planck Research School, Max Planck Institute for Chemical Ecology, Jena, Germany
Research theme: The evolution of metabolic cross-feeding interactions among bacteria
2012 – 2015 Research fellow, Chemical Biology Group, South Asian University, New Delhi, India
Research theme: Dissecting molecular intricacies and functional role of polyketide derived cellular lipids in
mycobacteria.
2009 – 2012 Master of Technology (M.Tech.) in Biotechnology, Gautam Buddha University, Greater Noida, India.
Master thesis: Investigation of conserved molecular interactions in fatty acyl-AMP ligases (FAALs) and fatty
acyl-CoA ligases (FACLs).
2006 – 2009 B.Sc. Life Sciences, University of Delhi, SGTB Khalsa College, New Delhi, India
International Max Planck Research School, Max Planck Institute for Chemical Ecology, Jena, Germany
Research theme: The evolution of metabolic cross-feeding interactions among bacteria
2012 – 2015 Research fellow, Chemical Biology Group, South Asian University, New Delhi, India
Research theme: Dissecting molecular intricacies and functional role of polyketide derived cellular lipids in
mycobacteria.
2009 – 2012 Master of Technology (M.Tech.) in Biotechnology, Gautam Buddha University, Greater Noida, India.
Master thesis: Investigation of conserved molecular interactions in fatty acyl-AMP ligases (FAALs) and fatty
acyl-CoA ligases (FACLs).
2006 – 2009 B.Sc. Life Sciences, University of Delhi, SGTB Khalsa College, New Delhi, India
Honours and Awards
2018 Oeiras travel grant for IGC Symposium 2018: Microbial Eco-Evolutionary Dynamics, Oeiras, Portugal
2015 German Research Foundation (DFG) research fellowship for PhD
2013 Junior Research Fellowship, Department of Biotechnology, Government of India
2012 GATE Biotechnology, Government of India
2015 German Research Foundation (DFG) research fellowship for PhD
2013 Junior Research Fellowship, Department of Biotechnology, Government of India
2012 GATE Biotechnology, Government of India
Oral Presentations
- Giri S. Experimental evolution of metabolic cross-feeding interactions in bacteria (Max Planck Institute for Chemical Ecology, Department meeting, Frohberg, Germany, May, 2016)
- Giri S. Bacterial nepotism: Does high relatedness favour the evolution of metabolic cross-feeding? (Progress report meeting the Special Priority Program SPP1617 Phenotypic Heterogeneity and Sociobiology of Bacterial Populations, Düsseldorf, Germany, April, 2016)
Poster Presentations
- Metabolism first: cross-feeding in bacteria is not dependent on phylogeny (IGC Symposium 2018, Microbial Eco-Evolutionary Dynamics, Oeiras, Portugal, October 2018)
- Bacterial nepotism: Does cross-feeding correlate with phylogenetic distance in bacteria? (ESEB-STN workshop, Experimental approaches to test for coevolution, CNRS campus, Gif-sur-Yvette, France, April 2018)
- Does cross-feeding correlate with phylogenetic distance in bacteria? (Progress report meeting the Special Priority Program SPP1617, Phenotypic Heterogeneity and Sociobiology of Bacterial Populations, Gottingen, Germany, March 2018)
- Better together: Experimental coevolution of metabolic cross-feeding among bacteria (Progress report meeting the Special Priority Program SPP1617, Phenotypic Heterogeneity and Sociobiology of Bacterial Populations, Munich, Germany, March 2017)
- Experimental coevolution of metabolic cross-feeding among bacteria. (IMPRS Symposium, MPI for Chemical Ecology, Jena, Germany, March 2017)
- With a little help from my friends: Does high relatedness favour the evolution of metabolic cross-feeding? (Discussion Meeting on Conflict and Cooperation in Cellular Populations (CCCP), NCBS-INSTEM CAMPUS, Bangalore, India, October 2016)
- Why make it when you can just take it? The evolution of metabolic cross-feeding interactions in bacteria. (ICE Symposium, MPI for Chemical Ecology, Jena, Germany, September 2016)
- Mechanistic versatility of Corynebacterineae Type III polyketide synthases. (Annual Conference 2016 of the Association for General and Applied Microbiology (VAAM), Jena, Germany, March 2016)
- Diversity of polyketide machinery in complex mycobacterial lipid biosynthesis. (5th International Singapore Lipid Symposium 2014 (iSLS5), National University of Singapore, Singapore, March 2014)
- Molecular machines in natural product biosynthesis. (International Conference on "Global IPR system and WTO Issues (GIPRS-2013)” Meerut, India, September 2013)
Courses, workshops and conferences
- ESEB-STN workshop, Experimental approaches to test for coevolution, CNRS campus, Gif-sur-Yvette, France, April 2018
- Evolutionary Biology Workshop in the Alps, Villa Cassel, Riederalp, Switzerland, June 2017
- IMPRS course: The Basics of Light and Fluorescence Microscopy, speaker: Dr. Veit Grabe, February 2017
- IMPRS course: Introduction to Basic Statistics and R, speaker: Dr. Grit Kunert, August- September 2016
- IMPRS course: Experimental Design Workshop, speaker: Andrew Davis, June 2016
- IMPRS course: Communication - How to Manage Your Supervisors, speaker: Dr. Alexander Schiller, Dr. Daniel Mertens, May 2016
- JSMC Course: Statistics in everyday research, organizer: Statcon, October 2015
- JSMC Course: Microbial communities-insight into biofilms, speaker: Dr. Akos T. Kovacs, September 2015
- Indo-German Workshop on Chemical Biology of Infectious Diseases at National Institute of Immunology (NII-DBT), New Delhi India, January 2014
- SYSCON conference on Interfacing Basic and translational research organized by All Indian Institute of Medical Sciences (AIIMS), India, August 2013
- Workshop on Metabolomics Using High-Resolution Mass Spectrometer at ABSCIEX Centre of Excellence, Gurgaon, India, November 2013
- Workshop on qPCR, HPLC experimental design and data analysis from ILS Bioservices, Gurgaon, India, June 2011
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