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Dr. Samuel H. A. von der Dunk
Senior postdoc
Department of Ecology
School of Biology/ Chemistry
University of Osnabrück
Barbarastrasse 13
49076 Osnabrück, Germany
Tel: +49 541 969-2908
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Research interests
I am a theoretical biologist fascinated by life’s complexity and the evolutionary processes that shape this complexity. I have a background in computational modelling and bioinformatics, and an affinity for statistical physics. In my current role as postdoc in the Christian Kost lab, I aim to integrate informational and metabolic perspectives on the evolution of cellular and genomic complexity (see group website).
Education and Scientific Career
Since 2026 Senior postdoc at University of Osnabrück.
2023 – 2026 Postdoc at University of Oxford with Ard A. Louis.
2018 – 2023 Doctoral (PhD) at Utrecht University with Berend Snel & Paulien Hogeweg.
2016 – 2018 Graduate (MSc) Molecular and Cellular Life Sciences at Utrecht University.
2012 – 2016 Undergraduate (BSc) Biology at Utrecht University.
2023 – 2026 Postdoc at University of Oxford with Ard A. Louis.
2018 – 2023 Doctoral (PhD) at Utrecht University with Berend Snel & Paulien Hogeweg.
2016 – 2018 Graduate (MSc) Molecular and Cellular Life Sciences at Utrecht University.
2012 – 2016 Undergraduate (BSc) Biology at Utrecht University.
Publications
2025 Von der Dunk, S. H. A., Dingle, K., Louis, A. A., Snel, B. and Hogeweg, P. (2025). Natural protein structures have evolved exceptional robustness to mutations. bioRxiv, 2025.08.27.672565.
2025 Von der Dunk, S. H. A., Martin, N. S., Dingle, K. and Louis, A. A. (2025). RNA secondary structures are conserved but random. bioRxiv, 2025.08.18.670923.
2025 Malone, J. S., Martin, N. S., Von der Dunk, S. H. A., Davalos, L. M. and Louis, A. A. (2025). Developmental bias explains the evolutionary trend towards simple leaf shapes. bioRxiv, 2025.08.17.670617.
2025 Zania, A., Hogeweg, P. and Von der Dunk, S. H. A. (2025). The risk of sexual reproduction promotes the evolution of regulation between host and symbiont. bioRxiv, 2025.07.30.667627.
2023 Von der Dunk, S. H. A., Hogeweg, P. and Snel, B. (2023). Intracellular signaling in proto-eukaryotes evolves to alleviate regulatory conflicts of endosymbiosis. PloS Computational Biology, 20(2): e1011860.
2023 Von der Dunk, S. H. A., Hogeweg, P. and Snel, B. (2023). Obligate endosymbiosis explains genome expansion during eukaryogenesis. Communications Biology, 6: 777.
2023 Vosseberg, J., Stolker, D., Von der Dunk, S. H. A. and Snel, B. (2023). Integrating phylogenetics with intron positions illuminates the origin of the spliceosome. Molecular biology and evolution, 40(1): msad011.
2022 Von der Dunk, S. H. A., Snel, B. and Hogeweg, P. (2022). Evolution of Regulatory Complexity for Cell-cycle Control. Genome biology and evolution, 14(5): evac056.
2020 Von der Dunk, S. H. A. and Snel, B. (2020). Recurrent sequence evolution after independent gene duplication. BMC evolutionary biology, 20:98.
2017 Von der Dunk, S. H. A., Colizzi, E. and Hogeweg, P. (2017). Evolutionary conflict leads to innovation: symmetry breaking in a spatial model of RNA-like replicators. Life, 7(4): 43.
2025 Von der Dunk, S. H. A., Martin, N. S., Dingle, K. and Louis, A. A. (2025). RNA secondary structures are conserved but random. bioRxiv, 2025.08.18.670923.
2025 Malone, J. S., Martin, N. S., Von der Dunk, S. H. A., Davalos, L. M. and Louis, A. A. (2025). Developmental bias explains the evolutionary trend towards simple leaf shapes. bioRxiv, 2025.08.17.670617.
2025 Zania, A., Hogeweg, P. and Von der Dunk, S. H. A. (2025). The risk of sexual reproduction promotes the evolution of regulation between host and symbiont. bioRxiv, 2025.07.30.667627.
2023 Von der Dunk, S. H. A., Hogeweg, P. and Snel, B. (2023). Intracellular signaling in proto-eukaryotes evolves to alleviate regulatory conflicts of endosymbiosis. PloS Computational Biology, 20(2): e1011860.
2023 Von der Dunk, S. H. A., Hogeweg, P. and Snel, B. (2023). Obligate endosymbiosis explains genome expansion during eukaryogenesis. Communications Biology, 6: 777.
2023 Vosseberg, J., Stolker, D., Von der Dunk, S. H. A. and Snel, B. (2023). Integrating phylogenetics with intron positions illuminates the origin of the spliceosome. Molecular biology and evolution, 40(1): msad011.
2022 Von der Dunk, S. H. A., Snel, B. and Hogeweg, P. (2022). Evolution of Regulatory Complexity for Cell-cycle Control. Genome biology and evolution, 14(5): evac056.
2020 Von der Dunk, S. H. A. and Snel, B. (2020). Recurrent sequence evolution after independent gene duplication. BMC evolutionary biology, 20:98.
2017 Von der Dunk, S. H. A., Colizzi, E. and Hogeweg, P. (2017). Evolutionary conflict leads to innovation: symmetry breaking in a spatial model of RNA-like replicators. Life, 7(4): 43.
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